We scored likelihoods from the model using experimental tests of protein function. We found that if a base pair has high likelihood under Evo, then that base pair is likely to preserve or improve the protein’s function. But if that base pair has low likelihood, then putting that base pair into a protein sequence will… Continue reading The Poetry Fan Who Taught an LLM to Read and Write DNA
How Noether’s Theorem Revolutionized Physics
But symmetries go beyond shape. Imagine you do an experiment, then you move 10 meters to the left and do it again. The results of the experiment don’t change, because the laws of physics don’t change from place to place. This is called translation symmetry. Now wait a few days and repeat your experiment again.… Continue reading How Noether’s Theorem Revolutionized Physics
Why Trump’s Anti-DEI Order Is Both Radical and Rooted in Civil Rights Law
Marc Morial, president of the National Urban League, convened a panel of civil rights leaders last month to assail President Donald Trump’s executive order on “ending illegal discrimination and restoring merit-based opportunity.” The so-called anti-DEI order, Morial claimed, was an effort to “reverse the gains of the last seventy years.” Marc Morial: His National Urban League… Continue reading Why Trump’s Anti-DEI Order Is Both Radical and Rooted in Civil Rights Law
Cosmologists Try a New Way to Measure the Shape of the Universe
There are slight variations in the CMB: Some spots on the last scattering surface (where the CMB photons originated) are a bit warmer than average, while others are a bit cooler. These patterns were created by sound waves propagating through the plasma of the early universe. The waves themselves were triggered by minute quantum fluctuations… Continue reading Cosmologists Try a New Way to Measure the Shape of the Universe
Parents Move Right, Pundits Panic, While Trump Delivers on Education
While progressive voters, Kamala Harris’s campaign team, and the Pod Save America guys wax poetic and point fingers about November’s election results, President Trump is delivering on his campaign promises to parents—firehose style. My sense is that most in the pundit class still don’t grasp how much parents with school-aged children influenced the election–shifting 7 points… Continue reading Parents Move Right, Pundits Panic, While Trump Delivers on Education
Epic Gravity Lens Lines Up Seven-Galaxy View
November 4, 2024 2 min read Epic Gravity Lens Lines Up Seven-Galaxy View A galaxy cluster bends light from seven background galaxies around it, letting astronomers peer into space and time By Tom Metcalfe edited by Sarah Lewin Frasier The Carousel Lens (center) bends the light of seven background galaxies. DESI Legacy Imaging Surveys/LBNL/DOE &… Continue reading Epic Gravity Lens Lines Up Seven-Galaxy View
Mysterious Experiences 3
Mysterious Experiences 3 < !- end of Google Analytics Code Snippet by GA4WP–> // tabnab protection window.addEventListener(‘load’, function () { // make all links have rel=”noopener noreferrer” document.querySelectorAll(‘a[target=”_blank”]’).forEach(link => { link.setAttribute(‘rel’, ‘noopener noreferrer’); }); }); ]]> Podcast: Download MYS350: To celebrate their 350th regular episode, Jimmy Akin and Dom Bettinelli look at more of listener’s… Continue reading Mysterious Experiences 3
Trump’s Attack on Debanking Is a Win for Conservatives’ Financial Freedom
At long last, the quiet weaponization of financial institutions against conservative and religious Americans has been directly called out by the country’s highest elected official. “Many conservatives complain that the banks are not allowing them to do business within the bank,” President Trump said to Bank of America CEO Brian Moynihan at a World Economic… Continue reading Trump’s Attack on Debanking Is a Win for Conservatives’ Financial Freedom
How Does Life Happen When There’s Barely Any Light?
Their estimate is a conservative one, he added, and it’s possible even fewer photons got through. “The ice cover is quite heterogeneous,” he explained. Because some parts of the sheet might allow more light through than others, the research team selected the upper thresholds of their light measurements. “In the end there’s some variety, and… Continue reading How Does Life Happen When There’s Barely Any Light?
Chicago Can’t Afford to Dance to All That Lefty Teacher Union Jazz
Above, déjà vu all over again: There’s a growing possibility of a teachers’ strike in Chicago like this one in 2012, as the city exemplifies school troubles rocking the nation. By Vince Bielski, RealClearInvestigationsFebruary 5, 2025 After nasty clashes involving character assassinations and a mass resignation, a showdown is drawing closer in Chicago between the… Continue reading Chicago Can’t Afford to Dance to All That Lefty Teacher Union Jazz